Radiochemotherapy in the Management of Gastroesophageal Junction Tumours: Basic Evidences in the Neoadjuvant Setting

In recent years the incidence of gastroesophageal junction (GEJ) tumors has been rapidly increasing. Many trials have investigated the role of preoperative radiochemotherapy for this specific subgroup. In past, GEJ tumors were sometimes considered either esophageal or gastric cancer, due to their anatomical location. Purpose of this paper is to elucidate the benefit of radiotherapy in combination with concurrent chemotherapy in neoadjuvant setting, reviewing the literature by the point of view of the recent classification provided for GEJ tumors. *Corresponding author: Cellini F, Cattedra of Radiation Oncology, University Campus Bio-Medico, Rome, Italy, Tel: +39-622541420; E-mail: [email protected] Received August 29, 2013; Accepted October 23, 2013; Published October 30, 2013 Citation: Cellini F, Fiore M, Mattiucci G (2013) Radiochemotherapy in the Management of Gastroesophageal Junction Tumours: Basic Evidences in the Neoadjuvant Setting. J Gastroint Dig Syst 3: 148. doi: 10.4172/2161-069X.1000148 Copyright: © 2013 Cellini F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.